Utilizing genetics and proteomics to assess the role of antihypertensive drugs in human longevity and the underlying pathways: a Mendelian randomization study.

Published in: European heart journal. Cardiovascular pharmacotherapy (2024)

BBs, CCBs and vasodilators may prolong lifespan, with potential sex differences for BBs and CCBs. The role of CCBs in lifespan is partly mediated by CDH1. Prioritizing the potential protein targets can provide new insights into healthy aging.

Keyphrases

endothelial cells
blood pressure

risk assessment

climate change

amino acid