Inverse association of mortality and body mass index in patients with left ventricular systolic dysfunction of both ischemic and non-ischemic etiologies.
Tiffany L BrazileSuresh MulukutlaFloyd ThomaN A Mark EstesSandeep JainSamir F SabaPublished in: Clinical cardiology (2021)
Our results support the existence of an obesity paradox impacting all-cause mortality in patients with LVSD of ischemic and non-ischemic etiologies even after adjusting for LVEF and comorbidities. Additional research is needed to understand the effect of weight loss on survival once a diagnosis of LVSD is established.
Keyphrases
- weight loss
- left ventricular
- body mass index
- ischemia reperfusion injury
- heart failure
- cerebral ischemia
- metabolic syndrome
- bariatric surgery
- blood pressure
- oxidative stress
- type diabetes
- insulin resistance
- roux en y gastric bypass
- cardiovascular disease
- cardiovascular events
- risk factors
- mitral valve
- coronary artery disease
- hypertrophic cardiomyopathy
- gastric bypass
- skeletal muscle
- cardiac resynchronization therapy
- high fat diet induced
- aortic valve