METTL1 mediated tRNA m 7 G modification promotes leukaemogenesis of AML via tRNA regulated translational control.

Pan ZhaoLin XiaDan ChenWei XuHuanping GuoYinying XuBingbing YanXiao WuYuxia LiYunfang ZhangXi Zhang

Published in: Experimental hematology & oncology (2024)

Taken together, our study demonstrates the important role of METTL1/WDR4 in AML leukaemogenesis, which provides a promising target candidate for AML therapy.