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Diagnosing and staging epithelial ovarian cancer by serum glycoproteomic profiling.

Chirag DharPrasanna RamachandranGege XuChad PickeringTomislav ČavalMaurice WongRachel RiceBo ZhouApoorva SrinivasanPaul AiyetanChih-Wei ChuKaitlyn MoserThomas J HerzogAlexander Babatunde OlawaiyeFrancis JacobDaniel SerieKlaus LindpaintnerFlavio Schwarz
Published in: British journal of cancer (2024)
Blood glycopeptide biomarkers have the potential to distinguish benign from malignant pelvic masses, and early- from late-stage EOC. Glycosylation of circulating and tumor tissue proteins may be related. This study supports the hypothesis that blood glycoproteomic profiling can be used for EOC diagnosis and staging and it warrants further clinical evaluation.
Keyphrases
  • clinical evaluation
  • lymph node
  • single cell
  • pet ct
  • rectal cancer
  • magnetic resonance imaging
  • risk assessment
  • contrast enhanced
  • ultrasound guided