Characterization of hepatitis B and delta coinfection in Israel.
Rachel ShiraziDaniela RamAviya RakovskyEfrat BucrisYael GozlanYaniv LustigPninit Shaked-MishanOrit PicardYonat Shemer-AvniHaim Ben-ZviOra HalutzYoav LurieElla VeizmanMatthias CarlebachMarius BraunMichal Cohen- NaftalyAmir ShlomaiRifaat SafadiElla MendelsonElla H SklanZiv Ben-AriOrna MorPublished in: BMC infectious diseases (2018)
The overall significant prevalence of HDV (6.5%) mandates HDV RNA testing for all coinfected patients. Patients positive for HDV RNA (characterized by low HBV DNA blood levels) carried HDV genotype 1. Taken together, the significant HDV seroprevalence and the lack of effective anti-HDV therapy, necessitates strict clinical surveillance especially in patients with higher HDV viral loads and increased viral evolution.