Association between the development of sub-clinical cardiovascular disease and HIV reservoir markers in people with HIV on suppressive ART.

We report that PWH diagnosed with coronary artery atherosclerotic plaques display higher levels of HIV DNA compared to those without atherosclerotic plaques. In a multivariable prediction model that included 27 traditional and HIV-related risk factors, measures of HIV DNA were among the most important predictors of atherosclerotic plaque formation.