Thromboprophylaxis in congenital nephrotic syndrome: 15-year experience from a national cohort.

Laurence J DobbieAngela LambLucy EskellIan J RamageBen Christopher Reynolds

Published in: Pediatric nephrology (Berlin, Germany) (2020)

Achieving thromboprophylaxis in CNS is challenging. Similar numbers of patients achieved stable anticoagulation on warfarin and enoxaparin. Enoxaparin dosing was nearly double the recommended starting doses for secondary thromboprophylaxis. Bleeding events were all associated with supra-therapeutic anticoagulation.

Keyphrases

venous thromboembolism
direct oral anticoagulants
atrial fibrillation
end stage renal disease
newly diagnosed
ejection fraction
prognostic factors
quality improvement
patient reported outcomes
blood brain barrier