Longitudinal quantification of the gingival crevicular fluid proteome during progression from gingivitis to periodontitis in a canine model.
Ian J DavisAndrew W JonesAndrew J CreeseRuth StauntonJujhar AtwalIain L C ChappleStephen HarrisMelissa M GrantPublished in: Journal of clinical periodontology (2016)
This study demonstrates for the first time that proteins detected by mass spectrometry have potential to identify novel biomarkers for canine periodontal disease. Further work is required to validate additional biomarkers for a periodontitis diagnostic.