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Congenital Pseudarthrosis of the Tibia Associated With Cleidocranial Dysostosis: Case Report and Literature Review.

Philip K McClureJeanne M FranzoneJohn E Herzenberg
Published in: JBJS case connector (2021)
Understanding, treatment, and surgical protocol of CPT have changed considerably since this comorbidity was last reported. Updates include synostosis, periosteal grafting, the use of bone morphogenetic protein, and bisphosphonates. Our case varies from the previous in associated disorder and family history. The relationship between CBFA1 and RUNX2 genes may hold the key, but further study is needed.
Keyphrases
  • transcription factor
  • genome wide
  • dna methylation
  • bioinformatics analysis