Eigen-Epistasis for detecting gene-gene interactions.

Virginie StanislasCyril DalmassoChristophe Ambroise

Published in: BMC bioinformatics (2017)

The method is tested against two recent alternative proposals from the literature using synthetic data, and shows good performances in different settings. We demonstrate the power of our approach by detecting new gene-gene interactions on three genome-wide association studies.

Keyphrases

copy number
genome wide
systematic review
genome wide association
gene expression
machine learning
electronic health record
deep learning