Time to Introduce Nerve Density in Cancer Histopathological Assessment.
Ralph A BradshawChen Chen JiangPublished in: Clinical cancer research : an official journal of the American Association for Cancer Research (2023)
The density of nerves in the tumor microenvironment is increasingly reported to be associated with worse clinical outcome in various cancers. Therefore, it is time to consider the assessment of nerve density in clinical cancer pathology, and interestingly, the development of artificial intelligence may facilitate this clinical translation.