Antimicrobial effects of mesenchymal stem cells primed by modified LPS on bacterial clearance in sepsis.
Pardis SaeediRaheleh HalabianAbbas Ali Imani FooladiPublished in: Journal of cellular physiology (2018)
LPS preconditioning provides an innovative strategy for evolving functional and biological properties of MSCs and ameliorates the survival rate of the mouse model of sepsis after MSC transplantation, protects cells from apoptosis and organ damages, and evaluates therapeutic properties, including immunemodulatory.
Keyphrases
- mesenchymal stem cells
- mouse model
- septic shock
- umbilical cord
- inflammatory response
- acute kidney injury
- intensive care unit
- anti inflammatory
- cell therapy
- oxidative stress
- staphylococcus aureus
- bone marrow
- endoplasmic reticulum stress
- ischemia reperfusion injury
- cerebral ischemia
- brain injury
- subarachnoid hemorrhage