Differential arterial and venous endothelial redox responses to oxidative stress.
Bandana ShresthaPriya K PrasaiAmir M KaskasAnkur KhannaVijay LetchumanSunjay LetchumanJonathan Steven AlexanderA Wayne OrrMatthew D WoolardChristopher B PattilloPublished in: Microcirculation (New York, N.Y. : 1994) (2018)
Arterial and venous endothelial cells exhibit differential responses to oxidant stress, and decreases in GSH:GSSG are more exacerbated in venous endothelial cells. Specific pathogenesis in these vascular conduits, with respect to oxidant stress handling, warrants further study, especially considering surgical interventions such as Coronary artery bypass grafting that use both interchangeably.