Mutational profile of ZBTB16-RARA-positive acute myeloid leukemia.

Emiliano FabianiLaura CicconiAnna Maria NardozzaAntonio CristianoMarianna RossiTiziana OttoneGiulia FalconiMariadomenica DivonaAnna Maria TestiOmbretta AnnibaliRoberto CastelliVladimir Lj LazarevicEduardo RegoPau MontesinosJordi EsteveAdriano VendittiMatteo Della PortaWilliam ArceseFrancesco Lo-CocoMaria Teresa Voso

Published in: Cancer medicine (2021)

Our data suggest the association of mutations of the ARID1A gene and of the other members of the SWI/SNF chromatin remodeling complexes with ZBTB16-RARA+AMLs, where they may support the peculiar disease phenotype.

Keyphrases

acute myeloid leukemia
genome wide
gene expression
dna damage
electronic health record
transcription factor
copy number
allogeneic hematopoietic stem cell transplantation
big data
dna methylation
genome wide identification
machine learning
data analysis
artificial intelligence