Acute bacterial skin and skin structure infections in pediatric patients: potential role of dalbavancin.
Lorenzo VolpicelliMario VendittiAlessandra OlivaPublished in: Expert review of anti-infective therapy (2023)
Many of the therapeutic options available at the moment are characterized by need for hospitalization or repeated intravenous infusion, safety issues, possible drug-drug interactions and reduced efficacy on MDRs. Dalbavancin, the first long-acting molecule with strong activity against methicillin-resistant and also many vancomycin-resistant pathogens, represented a game changer for adult ABSSSI. In pediatric settings the available literature is still limited but a growing body of evidence supports dalbavancin use in children with ABSSSI, demonstrating this drug to be safe and highly efficacious.
Keyphrases
- methicillin resistant staphylococcus aureus
- drug induced
- soft tissue
- staphylococcus aureus
- wound healing
- systematic review
- liver failure
- young adults
- adverse drug
- high dose
- respiratory failure
- gram negative
- emergency department
- antimicrobial resistance
- intensive care unit
- hepatitis b virus
- acute respiratory distress syndrome