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MARRIAGE: A Randomized Trial of Moxonidine Versus Ramipril or in Combination With Ramipril in Overweight Patients With Hypertension and Impaired Fasting Glucose or Diabetes Mellitus. Impact on Blood Pressure, Heart Rate and Metabolic Parameters.

Paul ValensiSelim Jambart
Published in: Journal of cardiovascular pharmacology and therapeutics (2024)
Moxonidine 0.4 mg and ramipril 5 mg were equally effective on BP lowering and were well tolerated and mostly metabolically neutral either as monotherapies or in combination. HR was lowered on moxonidine treatment.
Keyphrases
  • heart rate
  • blood pressure
  • blood glucose
  • heart rate variability
  • hypertensive patients
  • weight loss
  • physical activity
  • type diabetes