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Fusion oncogenes in patients with locally advanced or distant metastatic differentiated thyroid cancer.

Gaoda JuYuqing SunHao WangXin ZhangZhuanzhuan MuDi SunLisha HuangRuijue LinTao XingWuying ChengJun LiangYan-Song Lin
Published in: The Journal of clinical endocrinology and metabolism (2023)
Fusion oncogenes were more prevalent in pediatric DTCs than in their adult counterparts and were associated with pediatric RAI-refractoriness, while in adult DTCs, TERT mutation was the dominant genetic contributor to RAI-refractoriness rather than fusion oncogenes.
Keyphrases
  • squamous cell carcinoma
  • locally advanced
  • childhood cancer
  • small cell lung cancer
  • rectal cancer
  • neoadjuvant chemotherapy
  • lymph node
  • radiation therapy
  • genome wide
  • gene expression
  • copy number
  • free survival