Performance of the PRIMaCY sudden death risk prediction model for childhood hypertrophic cardiomyopathy: implications for implantable cardioverter-defibrillator decision-making.

Gabrielle Norrish Alexandros Protonotarios Maria Stec Olga BoletiElla FieldElena Cervi Perry Mark Elliott Juan Pablo Pablo Kaski

Published in: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology (2023)

Although PRIMaCY has a similar discriminatory ability to that reported for HCM Risk-Kids, estimated risk estimates did not correlate well with observed risk. A higher proportion of patients met implantable cardioverter-defibrillator thresholds using PRIMaCY model compared with HCM Risk-Kids. This has important clinical implications as these patients will be exposed to a lifetime risk of complications and inappropriate therapies.

Keyphrases

hypertrophic cardiomyopathy
end stage renal disease
newly diagnosed
ejection fraction
chronic kidney disease
peritoneal dialysis
decision making
left ventricular
prognostic factors
risk factors
patient reported outcomes
patient reported