Long-term use of proton pump inhibitors, dose-response relationship and associated risk of ischemic stroke and myocardial infarction.
Thomas S G SehestedT A GerdsE L FosbølP W HansenM G CharlotN CarlsonM A HlatkyC Torp-PedersenG H GislasonPublished in: Journal of internal medicine (2017)
Use of PPIs was associated with increased risks of first-time ischemic stroke and MI, particularly amongst long-term users and at high doses.