Genetic predisposition to differentiated thyroid cancer in the Polish population.

Martyna BorowczykMateusz SypniewskiJoanna SzydaMałgorzata BraszkaKatarzyna ZiemnickaMarek RuchałaMichalina OszywaZbigniew J KrólPaula Dobosz

Published in: Polish archives of internal medicine (2024)

Even though the Polish population is genetically similar to the other European populations, there are significant differences in variant frequencies contributing to the disease development and progression, such as those in the RET, CHEK2, BRCA1, SLC26A4, or TERT genes. Further studies are needed to identify genomic variants associated directly with DTC.

Keyphrases

copy number
genome wide
papillary thyroid
dna methylation
squamous cell
bioinformatics analysis