In Silico Model for Predicting CYP2D6-Mediated Drug-Drug Interactions.
Roberto LozanoAlberto FrutosAlejandro Martinez
Published in: Current reviews in clinical and experimental pharmacology (2022)
According to our results, knowledge of the inhibition constant and therapeutic range (or its plasma levels if disponible) of the inhibitor would be sufficient to determine the intensity and clinical relevance of a CYP2D6-mediated DDI.