Circulating plasma cells as a predictive biomarker in Multiple myeloma: an updated systematic review and meta-analysis.

Qun LiLisha AiLiping ZuoJunying LiFei ZhaoAoshuang XuBo ZhangLi CaiHan Yan Chunyan Sun

Published in: Annals of medicine (2024)

Our meta-analysis confirmed that the increased number of CPCs had a negative impact on the PFS and OS of MM patients. Therefore, CPCs could be a promising prognostic biomarker that helps with risk stratification and disease monitoring.

Keyphrases

systematic review
multiple myeloma
induced apoptosis
ejection fraction
newly diagnosed
prognostic factors
meta analyses
oxidative stress
cell proliferation
signaling pathway