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Behavioral testing of minipigs transgenic for the Huntington gene-A three-year observational study.

Verena SchuldenzuckerRobin SchubertLisa M MuratoriFrauke FreisfeldLorena RiekeTamara MatheisSarah SchramkeJan MotlikNicole KemperUte RadespielRalf Reilmann
Published in: PloS one (2017)
The assessment battery presented offers measures in all domains relevant for HD and can be applied in long-term phenotyping studies with tgHD minipigs. The observation of this cohort should be continued to explore the timeline of phenotype development and provide information for future interventional studies.
Keyphrases
  • case control
  • high throughput
  • genome wide
  • current status
  • gene expression
  • single cell
  • clinical evaluation