Ketamine for catatonia: A novel treatment for an old clinical challenge? A systematic review of the evidence.

Ana Teresa Caliman-FontesFlávia VieiraGustavo C LealBeatriz A CarneiroYana Quarantini-AlvimTaiane V AndradeRodrigo P MelloAry GadelhaAcioly L T LacerdaLucas C Quarantini

Published in: Schizophrenia research (2024)

Challenging the conventional contraindication of ketamine in psychotic disorders, current evidence highlights its potential efficacy, particularly in treating catatonia. Pending further research, we advocate reevaluating this contraindication, as it may offer a promising therapeutic option, especially for challenging cases. Preliminary evidence suggests potentially greater benefits for catatonic patients with underlying mood disorders compared to primary psychotic disorders.

Keyphrases

bipolar disorder
pain management
depressive symptoms
chronic pain
replacement therapy
smoking cessation