Differential Binding of Autoantibodies to MOG Isoforms in Inflammatory Demyelinating Diseases.

Kathrin SchandaPatrick PeschlMagdalena LerchBarbara SeebacherSwantje MindorfNora RitterMonika ProbstHarald HegenFranziska Di PauliEva-Maria WendelChristian LechnerMatthias BaumannSara MariottoSergio FerrariAlbert SaizMichael FarrellMaria Isabel S LeiteSarosh R IraniJacqueline PalaceAndreas LutterottiTania KümpfelSandra VukusicRomain MarignierPatrick J WatersKevin RostasyThomas BergerChristian ProbstRomana HöftbergerMarkus Reindl

Published in: Neurology(R) neuroimmunology & neuroinflammation (2021)

The novel finding of differential MOG isoform binding patterns could inform future studies on the refinement of MOG-IgG assays and the pathophysiologic role of MOG-IgG.

Keyphrases

oxidative stress
dna binding
binding protein
high throughput
transcription factor