Activating AMP-activated Protein Kinase Mediates Fibroblast Growth Factor 1 Protection from Nonalcoholic Fatty Liver Disease in Mice.
Qian LinZhifeng HuangGenxiang CaiXia FanXiaoqing YanZhengshuai LiuZehua ZhaoJingya LiJia LiHongxue ShiMaiying KongMing-Hua ZhengDaniel J ConklinPaul N EpsteinA Wintergerst KupperMoosa MohammadiLu CaiXiaokun LiYu LiYi TanPublished in: Hepatology (Baltimore, Md.) (2020)
These findings indicate that FGF1△HBS is effective for preventing and reversing liver steatosis and steatohepatitis and acts by activation of AMPK via hepatocyte FGFR4.
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