A dual tracer [ 11 C]PBR28 and [ 18 F]FDG microPET evaluation of neuroinflammation and brain energy metabolism in murine endotoxemia.
Santhoshi P PalandiraJoseph CarrionLauren TureckiAidan FalveyQiong ZengHui LiuTea TsaavaDov HerschbergMichael BrinesSangeeta S ChavanEric H ChangAn VoYilong MaChristine N MetzYousef Al-AbedKevin J TraceyValentin A PavlovPublished in: Bioelectronic medicine (2022)
F]FDG dual tracer microPET imaging for assessing neuroinflammation and brain metabolic alterations in conditions "classically" characterized by peripheral inflammatory and metabolic pathogenesis.
Keyphrases
- pet imaging
- positron emission tomography
- cerebral ischemia
- lps induced
- resting state
- pet ct
- computed tomography
- white matter
- traumatic brain injury
- lipopolysaccharide induced
- high resolution
- functional connectivity
- cognitive impairment
- subarachnoid hemorrhage
- inflammatory response
- oxidative stress
- brain injury
- multiple sclerosis