1,4-Bisvinylbenzene-Bridged BODIPY Dimers for Fluorescence Imaging in the Second Near-Infrared Window.

Herein, we report a class of 1,4-bisvinylbenzene-bridged BODIPY dimers with fluorescence emission in the second near-infrared window (NIR-II, 1000-1700 nm). These dyes show excellent NIR-II fluorescence properties and can be easily functionalized to achieve good water-solubility or tumor-targeting ability. In vivo imaging results demonstrate that these dyes have high resolution and deep-penetration NIR-II imaging ability, which enable them to be used as promising NIR-II imaging agents.