A sensitive method for analyzing fluconazole in extremely small volumes of neonatal serum.

Jumpei SaitoAyano TanzawaYuka KojoHidehiko MaruyamaTetsuya IsayamaKensuke ShojiYushi ItoAkimasa Yamatani

Published in: Journal of pharmaceutical health care and sciences (2020)

Fluconazole was able to be detected in an extremely small volume (10 μL) of serum from neonates receiving fosfluconazole. The method presented here can be used to quantify fluconazole concentrations for pharmacokinetic studies of the neonatal population by using scavenged samples.

Keyphrases

candida albicans
low birth weight
case control