Palladium-catalyzed allylation of tautomerizable heterocycles with alkynes.
Chuan-Jun LuDong-Kai ChenHong ChenHong WangHongwei JinXifu HuangJianrong GaoPublished in: Organic & biomolecular chemistry (2017)
A method for the allylic amidation of tautomerizable heterocycles was developed by a palladium catalyzed allylation reaction with 100% atom economy. A series of structurally diverse N-allylic substituted heterocycles can be synthesized in good yields with high chemo-, regio-, and stereoselectivities under mild conditions.