Serum N-Glycome analysis reveals pancreatic cancer disease signatures.
Gerda C M VreekerRanda G Hanna-SawiresYassene MohammedMarco R BladergroenSimone NicolardiViktoria DotzJan NoutaBert A BonsingWilma E MeskerYuri E M van der BurgtDana L E VergoossenRob A E M TollenaarPublished in: Cancer medicine (2020)
Serum N-glycome analysis revealed glycosylation differences that allow classification of PDAC patients from healthy controls. It was demonstrated that glycosylation traits rather than single N-glycan structures obtained in this clinical glycomics study can serve as a basis for further development of a blood-based diagnostic test.