Intestinal Barrier Dysfunction and Microbial Translocation in Patients with First-Diagnosed Atrial Fibrillation.

Leon BlöbaumMarco WitkowskiMax WegnerStella LammelPhilipp-Alexander SchenckeKai JakobsMarianna PucciniDaniela ReißnerDaniel SteffensUlf LandmesserUrsula RauchJulian Friebel

Published in: Biomedicines (2023)

Intestinal barrier dysfunction and microbial translocation accompany FDAF. Improving gut permeability and low-grade endotoxaemia might be a potential therapeutic approach to reducing the disease progression and cardiovascular complications in FDAF.

Keyphrases

low grade
high grade
microbial community
atrial fibrillation
oxidative stress
heart failure
endothelial cells
left atrial
oral anticoagulants
catheter ablation
risk factors
direct oral anticoagulants
left atrial appendage
venous thromboembolism