Characterization of localized macrophages in bronchiolitis obliterans after allogeneic hematopoietic cell transplantation.

Taiga KuroiNobuharu FujiiKoichi IchimuraKeisuke SeikeAkira YamamotoYui KambaraSeiichiro SugimotoShinji OtaniKyosuke SaekiHideaki FujiwaraHisakazu NishiomoriTakahiro OtoYoshinobu Maeda

Published in: International journal of hematology (2021)

Donor-derived M1-macrophages may be involved in the pathogenesis of the early-stage region of BOS. In addition, some macrophages in the late-stage region showed M2 polarization that might be involved in fibrosis.

Keyphrases

early stage
bone marrow
squamous cell carcinoma
radiation therapy
liver fibrosis
neoadjuvant chemotherapy