The serum miR-146b-5p levels might be a promising tool to be used as a non-invasive diagnostic biomarker for HCC. Our findings shed light on potential biomarkers for the diagnosis of HBV-HCC in terms of selected miRNAs. The target pathways of miR-146b-5p identified by our in-silico analysis to reveal the functional mechanism are "MAPK signaling pathways" and "Pathways in cancer."
Keyphrases
- hepatitis b virus
- signaling pathway
- bioinformatics analysis
- genome wide
- liver failure
- cell proliferation
- pi k akt
- papillary thyroid
- long non coding rna
- oxidative stress
- electronic health record
- molecular docking
- squamous cell
- long noncoding rna
- copy number
- big data
- squamous cell carcinoma
- epithelial mesenchymal transition
- single cell
- induced apoptosis
- genome wide identification
- transcription factor
- data analysis
- young adults