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Signal Detection of Adverse Events Associated with Trastuzumab in a Cohort of Elderly Patients with Breast Cancer.

Efstathia PolychronopoulouSharon H GiordanoLin-Na ChouXiaoying YuAshwani K Singal
Published in: The oncologist (2022)
We showed that claims data can be used to complement current ADE monitoring using common data mining methods with propensity score matching. Our analysis identified all expected ADEs associated with trastuzumab, and additional signals of valvular heart disorders.
Keyphrases
  • electronic health record
  • epidermal growth factor receptor
  • atrial fibrillation
  • big data
  • heart failure
  • health insurance
  • data analysis
  • middle aged
  • loop mediated isothermal amplification
  • label free