Contribution of Potentially Inappropriate Medications to Polypharmacy-Associated Risk of Mortality in Middle-Aged Patients: A National Cohort Study.

Jordan GuillotAmy C JusticeKirsha S GordonMelissa SkandersonAntoine ParienteJulien BezinChristopher T Rentsch

Published in: Journal of general internal medicine (2024)

PIMs were independently associated with increased mortality, and partially explained polypharmacy-associated mortality in middle-aged people. Other mechanisms of injury from polypharmacy should also be studied.

Keyphrases

middle aged
cardiovascular events
end stage renal disease
risk factors
ejection fraction
newly diagnosed
chronic kidney disease
peritoneal dialysis
prognostic factors
cardiovascular disease
emergency department
type diabetes
coronary artery disease
quality improvement
patient reported
drug induced