Effect of aspirin response signature gene expression on preterm birth and preeclampsia among women with lupus: a pilot study.
Amanda M EudyD VooraR A MyersM E B ClowsePublished in: Lupus (2019)
Our pilot study identified two candidate genes that are reflective of the platelet function response to aspirin. Further work is needed to determine the role of these genes in identifying women with lupus at high risk for preeclampsia and preterm delivery despite aspirin therapy.
Keyphrases
- preterm birth
- low dose
- gene expression
- low birth weight
- systemic lupus erythematosus
- cardiovascular events
- antiplatelet therapy
- gestational age
- early onset
- disease activity
- dna methylation
- anti inflammatory drugs
- genome wide
- pregnancy outcomes
- acute coronary syndrome
- rheumatoid arthritis
- type diabetes
- stem cells
- transcription factor
- atrial fibrillation
- cell therapy