Soluble ST2 as a New Oxidative Stress and Inflammation Marker in Metabolic Syndrome.
Ignacio RoyEva JoverLara MatillaVirginia AlvarezAmaya Fernández-CelisMaite BeunzaElena EscribanoAlicia GainzaRafael SadabaNatalia Lopez-AndreésPublished in: International journal of environmental research and public health (2023)
Circulating levels of sST2 are associated with oxidative stress and inflammation burden and may underlie the pathological remodeling and dysfunction of the heart in MS patients. Our results suggest that sST2 elevation precedes diastolic dysfunction, emerging as an attractive biotarget in MS.
Keyphrases
- oxidative stress
- metabolic syndrome
- diabetic rats
- ejection fraction
- dna damage
- ischemia reperfusion injury
- mass spectrometry
- end stage renal disease
- induced apoptosis
- multiple sclerosis
- ms ms
- newly diagnosed
- chronic kidney disease
- heart failure
- prognostic factors
- patient reported outcomes
- insulin resistance
- cardiovascular disease
- adipose tissue
- cardiovascular risk factors