Protective effects of desipramine on alveolar bone in experimental periodontitis.

Luciana Salles Branco de Almeida Gilson Cesar Nobre Franco Myrella Lessio Castro Mayana S Vieira Leonardo Victor Galvão Moreira Sheila Cavalca Cortelli Ana Lia Anbinder Toshihisa Kawai Pedro Luiz Rosalen

Published in: Journal of periodontology (2020)

Desipramine administration reduced alveolar bone loss as histologically observed, and modulated key bone remodeling and inflammatory mediators in rats with ligature-induced periodontitis.

Keyphrases

bone loss
diabetic rats
oxidative stress
high glucose
drug induced
postmenopausal women