Impact of sodium glucose cotransporter 2 inhibitor on histological features and glucose metabolism of non-alcoholic fatty liver disease complicated by diabetes mellitus.

Norio AkutaYusuke KawamuraChizuru WatanabeAkihiro NishimuraMinoru OkuboYasumichi MoriShunichirou FujiyamaHitomi SezakiTetsuya HosakaMasahiro KobayashiMariko KobayashiSatoshi SaitohFumitaka SuzukiYoshiyuki SuzukiYasuji AraseKenji IkedaHiromitsu Kumada

Published in: Hepatology research : the official journal of the Japan Society of Hepatology (2019)

A prospective study showed that SGLT2I for NAFLD complicated by DM improved histological features in connection with glucose metabolism. This trial was registered as clinical trial UMIN000018166.

Keyphrases

clinical trial
phase ii
phase iii
study protocol
glycemic control
open label
double blind
type diabetes
liver fibrosis
adipose tissue
insulin resistance
skeletal muscle
weight loss