Influence of ensitrelvir or nirmatrelvir/ritonavir on tacrolimus clearance in kidney transplant recipients: a single-center case series.
Hanako NaganawaYoshiki KatadaShunsaku NakagawaKeisuke UmemuraHiroki IshimuraMoto KajiwaraHiroki EndoMitsuhiro SugimotoYurie KatsubeKinuka KotaniSaki OhtaDaiki HiraMasahiro TsudaYuki KitaTakashi KobayashiTomohiro TeradaPublished in: Journal of pharmaceutical health care and sciences (2024)
These cases suggest that TAC administration should be discontinued during NMV/RTV treatment to maintain blood TAC levels within the therapeutic range, and a reduced TAC dose is sufficient during ESV treatment.
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