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Disruption of the Hippo pathway promotes the proliferation of childhood acute lymphoblastic leukemia cells, inhibits apoptosis and chemosensitivity.
Hao Jiang
Rui-Bo Zhang
Juan Peng
Lan Ren
Heng-Dong Wang
Published in:
Expert review of hematology (2024)
Disruption of the Hippo pathway attenuates the development of cALL by promoting cell proliferation while suppressing apoptosis and drug sensitivity.
Keyphrases
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cell cycle arrest
pi k akt
signaling pathway
acute lymphoblastic leukemia
cell death
induced apoptosis
endoplasmic reticulum stress
cell proliferation
oxidative stress
cell cycle
allogeneic hematopoietic stem cell transplantation
acute myeloid leukemia