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Primary Intraosseous Granular Cell Tumor of the Sphenoid and Central Skull Base in a Pediatric Patient.

Delaney SheehanBelinda MantleAshley KraftRandall CraverChristopher ArcementRenee GardnerEllen ZakrisDaniel Nuss
Published in: Fetal and pediatric pathology (2024)
GCT primarily involving the osseous sphenoid/skull base has not been previously reported in a child. Although mostly benign, some are aggressive, with malignant transformation in 1-2%. Surgery is the mainstay of treatment, but in the skull base this may be limited by adjacent critical structures. Decision-making is guided by anatomic extent, histology, and clinical behavior.
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