Risk factors for opioid toxicity requiring naloxone rescue in adults: a case-control study.

Kebede A BeyeneWilson ShenTerry MitchellScott GilsonStella KangDaniel LaiLiandra MisquittaAtifa SlaimankhelAmy Hai Yan Chan

Published in: International journal of clinical pharmacy (2022)

Increased risk of OSRD was associated with a higher OME, a higher serum creatinine level prior to OSRD episode, and opioid naivety. Our findings can inform policies that aim to prevent serious adverse effects related to opioids.

Keyphrases

chronic pain
pain management
public health
oxidative stress
uric acid