Exploring new frontiers in drug delivery with minimally invasive microneedles: fabrication techniques, biomedical applications and regulatory aspects.
Niha SultanaAyesha WaheedAsad AliSamreen JahanMohd AqilYasmin SultanaMohd MujeebPublished in: Expert opinion on drug delivery (2023)
With the availability of numerous materials at the disposal of pharmaceutical scientists; the microneedle-based drug delivery technology has offered significant interventions towards the management of chronic maladies including cardiovascular disorders, diabetes, asthma, mental depression, etc. As happens with any new technology there are concerns with MN also such as biocompatibility issues with the material used for the fabrication. Nevertheless, the pharmaceutical industry must strive for preparing harmless, efficient, and cost-effective MN based delivery systems for wider acceptance and patient compliance.
Keyphrases
- drug delivery
- minimally invasive
- tissue engineering
- cancer therapy
- type diabetes
- room temperature
- cardiovascular disease
- chronic obstructive pulmonary disease
- lung function
- case report
- mental health
- low cost
- drug release
- depressive symptoms
- metal organic framework
- physical activity
- transition metal
- glycemic control
- transcription factor
- robot assisted
- sleep quality
- skeletal muscle
- metabolic syndrome
- allergic rhinitis
- cystic fibrosis
- weight loss
- heavy metals
- ionic liquid
- air pollution