Visuospatial working memory in behavioural variant frontotemporal dementia: a comparative analysis with Alzheimer's disease using the box task.
David FoxeMuireann IrishJames CarrickSau Chi CheungHer TengJames R BurrellRoy P C KesselsOlivier PiguetPublished in: Journal of neurology (2024)
Our findings reveal significant visuospatial working memory impairments in bvFTD, albeit of lesser severity compared to disease-matched AD patients. The Box Task, a novel measure of visuospatial working memory, proved effective in differentiating between bvFTD and AD, outperforming many traditional neuropsychological measures. Overall, our findings highlight the utility of assessing visuospatial memory when differentiating between bvFTD and AD in the clinical setting.
Keyphrases
- working memory
- transcranial direct current stimulation
- end stage renal disease
- attention deficit hyperactivity disorder
- transcription factor
- chronic kidney disease
- binding protein
- peritoneal dialysis
- prognostic factors
- contrast enhanced
- genome wide
- cognitive decline
- magnetic resonance imaging
- gene expression
- magnetic resonance
- computed tomography
- dna methylation