Timely diagnosis and staging of non-alcoholic fatty liver disease using transient elastography and clinical parameters.
Christine ShiehDina L Halegoua-De MarzioMatthew L HungJonathan M FenkelSteven K HerrinePublished in: JGH open : an open access journal of gastroenterology and hepatology (2020)
Our study suggested that >25% of patients presenting to a specialist for NAFLD may have advanced fibrosis (F3-F4). Diabetes (A1c >6.6%) and AST >43 U/L were the most predictive in identifying NAFLD patients with advanced fibrosis on imaging. We proposed a formula that may be used to prioritize NAFLD patients at higher risk of having advanced fibrosis for specialist referral and imaging follow-up.