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Ameliorative Effect of D-Carvone against Hepatic Ischemia-Reperfusion-Induced Injury in Rats.

Maged Elsayed MohamedNancy S Younis
Published in: Life (Basel, Switzerland) (2022)
Rats pretreated with D-carvone exhibited hepato-protective actions against Hep I/R-induced damage via the downregulation of HMGB1, TLR4, NFκB, NLP3, associated inflammatory mediators, and apoptotic markers.
Keyphrases
  • oxidative stress
  • diabetic rats
  • high glucose
  • signaling pathway
  • immune response
  • cell proliferation
  • toll like receptor
  • nuclear factor
  • endothelial cells
  • pi k akt