Hyperresponsive Platelets and a Reduced Platelet Granule Release Capacity Are Associated with Severity and Mortality in COVID-19 Patients.

Fadel Muhammad Garishah Dana HuskensSetyo Gundi PramudoDessy AndrianiMila AstriliaRizky Akbar SentosaAndré J A M van der VenBas de LaatMuhammad Hussein GasemQuirijn de MastMark Roest

Published in: Thrombosis and haemostasis (2022)

Using an accessible agonist-induced platelet granule ATP release assay, we show that platelet hyper-responsiveness and reduced platelet GRC in COVID-19 patients were associated with critical illness and mortality.

Keyphrases

sars cov
cardiovascular events
high glucose
cardiovascular disease
oxidative stress
diabetic rats
endothelial cells
single cell