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Acetic acid-induced colitis modulating potential of total crude alkaloidal extract of Picralima nitida seeds in rats.

Sarah A Otu-BoakyeKofi Oduro YeboahEric Boakye-GyasiJames Oppong KyekyekuPrince D OkyereNewman Osafo
Published in: Immunity, inflammation and disease (2023)
It can be concluded that PNE attenuates intestinal oxidative and inflammatory damages following intrarectal acetic acid challenge. Thus, demonstrates potential for use in chronic intestinal inflammatory diseases such as ulcerative colitis.
Keyphrases
  • oxidative stress
  • ulcerative colitis
  • signaling pathway